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Polymorphism in Molecular Crystals : Second Edition
Most people are familiar with the fact that diamond and graphite are both composed only of carbon; yet they have very different properties which result from the very different structures of the two solids - they are polymorphs of carbon.Understanding the relationship between the structures and the properties of materials is of fundamental importance in developing and producing new materials with improved or new properties.The existence of polymorphic systems allows the direct study of the connection between structures and properties.This book provides grounding on the fundamental structural and energetic basis for polymorphism, the preparation and characterization of polymorphic substances and its importance in the specific areas of pharmaceuticals, pigments and high energy (explosive) materials.The closing chapter describes the intellectual property implications and some of the precedent patent litigations in which polymorphism has played a central role.The book contains over 2500 references to provide a ready entry into the relevant literature.
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Solid State Development and Processing of Pharmaceutical Molecules : Salts, Cocrystals, and Polymorphism
Solid State Development and Processing of Pharmaceutical Molecules A guide to the lastest industry principles for optimizing the production of solid state active pharmaceutical ingredients Solid State Development and Processing of Pharmaceutical Molecules is an authoritative guide that covers the entire pharmaceutical value chain.The authors—noted experts on the topic—examine the importance of the solid state form of chemical and biological drugs and review the development, production, quality control, formulation, and stability of medicines. The book explores the most recent trends in the digitization and automation of the pharmaceutical production processes that reflect the need for consistent high quality.It also includes information on relevant regulatory and intellectual property considerations.This resource is aimed at professionals in the pharmaceutical industry and offers an in-depth examination of the commercially relevant issues facing developers, producers and distributors of drug substances.This important book: Provides a guide for the effective development of solid drug forms Compares different characterization methods for solid state APIs Offers a resource for understanding efficient production methods for solid state forms of chemical and biological drugsIncludes information on automation, process control, and machine learning as an integral part of the development and production workflowsCovers in detail the regulatory and quality control aspects of drug development Written for medicinal chemists, pharmaceutical industry professionals, pharma engineers, solid state chemists, chemical engineers, Solid State Development and Processing of Pharmaceutical Molecules reviews information on the solid state of active pharmaceutical ingredients for their efficient development and production.
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What is dynamic polymorphism in object-oriented programming?
Dynamic polymorphism in object-oriented programming refers to the ability of a program to determine at runtime which method to invoke based on the actual type of object being referenced. This allows for flexibility and extensibility in the code, as different objects can exhibit different behaviors even if they belong to the same class hierarchy. Dynamic polymorphism is achieved through method overriding, where a subclass provides a specific implementation of a method defined in its superclass. This feature enables code reusability and promotes the principle of "write once, use many times" in object-oriented programming.
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What is polymorphism in Java programming?
Polymorphism in Java programming refers to the ability of a method to behave differently based on the object it is called on. This means that a single method can have different implementations depending on the type of object it is called on. This allows for more flexibility and reusability in code, as different objects can use the same method name but have different behaviors. Polymorphism is achieved through method overloading and method overriding in Java.
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How is identification done after VNTR polymorphism?
Identification after VNTR polymorphism is done by comparing the number of repeats in the variable number tandem repeats (VNTR) region of DNA between different individuals. This is typically done using a technique called polymerase chain reaction (PCR) to amplify the VNTR region, followed by gel electrophoresis to separate the DNA fragments based on size. The resulting pattern of DNA fragments, known as a DNA fingerprint, can then be compared between individuals to determine if they share a common genetic profile. This method is commonly used in forensic science and paternity testing to establish relationships between individuals based on their VNTR profiles.
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What is polymorphism in object-oriented programming?
Polymorphism in object-oriented programming refers to the ability of different objects to respond to the same message or method call in different ways. This means that objects of different classes can be treated as objects of a common superclass, allowing for more flexible and reusable code. Polymorphism allows for the implementation of methods that can work with objects of various types, making the code more adaptable and easier to maintain. This concept is a key feature of object-oriented programming and helps to promote code reusability and flexibility.
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What is the difference between polymorphism, allotropy, and pseudopolymorphism?
Polymorphism refers to the ability of a substance to exist in different crystal structures or forms. Allotropy, on the other hand, specifically refers to the existence of an element in multiple different forms, each with its own unique physical properties. Pseudopolymorphism, also known as solvomorphism, occurs when a substance appears to have different crystal forms due to the presence of solvent molecules within its crystal lattice. In summary, while polymorphism and allotropy refer to the different forms of a substance, pseudopolymorphism involves the influence of solvent molecules on the crystal structure.
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What is the difference between inheritance and polymorphism in Java?
Inheritance in Java allows a class to inherit properties and behaviors from another class, promoting code reusability. On the other hand, polymorphism allows objects of different classes to be treated as objects of a common superclass, enabling flexibility and extensibility in the code. Inheritance establishes an "is-a" relationship between classes, while polymorphism enables an object to take on multiple forms based on its context.
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What is the difference between substitution and polymorphism in Java?
Substitution refers to the ability to use a derived class object wherever a base class object is expected. This allows for code reusability and flexibility in the use of objects. Polymorphism, on the other hand, refers to the ability of a reference variable to point to different types of objects and invoke methods specific to those objects at runtime. In Java, polymorphism is achieved through method overriding, where a subclass provides a specific implementation of a method defined in its superclass. Overall, substitution is a concept related to inheritance and the use of derived classes, while polymorphism is a broader concept related to the ability of objects to take on different forms at runtime.
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What is an abstract class and how does polymorphism work in relation to it?
An abstract class is a class that cannot be instantiated on its own and is meant to be subclassed. It may contain abstract methods that must be implemented by its subclasses. Polymorphism allows objects of different classes that are related through inheritance to be treated as objects of the parent abstract class. This means that a method defined in the abstract class can be overridden in its subclasses, allowing different implementations of the same method to be called based on the type of object.
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